心臓再同期療法の効果をdyssynchrony解析で読む
国立循環器病研究センター放射線部
木曽啓祐
心電図同期心筋血流SPECT（GMPS）は近年、位相解析により左室収縮同期不全（dyssynchrony）の定量評価も可能となり、心臓再同期療法：C R T の適応決定にも利用されている。C R T の効果予測には左室dyssynchronyに加え組織障害の分布やCRTリード位置の重要性が認識され、GMPSはこれら重要項目の評価がほぼ全て可能であるため、その有用性が益々認識されてきている。
ECG-gated myocardial perfusion SPECT imaging (GMPS) has been utilized for the evaluation of extension and severity of tissue damage, and left ventricular (LV) functions. Recently, since quantitative analysis of LV dyssynchrony became available by GMPS, this modality is utilized for making decision of cardiac resynchronization therapy (CRT) indication. For the prediction of CRT response, not only the degree of LV dyssynchrony, but also the extension and location of tissue damage are necessary. From this standpoint, since GMPS is able to evaluate all of these important factors, advantage of this modality for CRT has been increasingly recognized.
